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在translational medicine這個產品中，有25篇Facebook貼文，粉絲數超過16萬的網紅中央研究院 Academia Sinica，也在其Facebook貼文中提到， #胰臟癌👫 #標靶治療🎯 開發 #抗癌藥物 15年磨一劍 想想那台 #小挖土機🚢 ⛏ 胰臟癌是相當棘手的癌症，確診時，患者的腫瘤細胞通常已經轉移，增加治療難度... 當年 #臺大醫院 醫師與本院 #李文華 院士分享臨床治療心得時，李院士意識到：若能結合臨床經驗與科學研究，有助於解決這...
　同時也有3部Youtube影片，追蹤數超過1,600的網紅運動營養師 楊承樺，也在其Youtube影片中提到，內容製作產出不易，你的 按讚訂閱分享 是支持我們的動力。 （發1篇影片要看超過20幾篇研究文獻再整理出最摘要建議，不幫我追蹤,按讚,分享出去， 安內甘丟 ~ XD ） 168間歇性斷食，運動營養師我也早已實行多年，但過去自己用的配法沒有說太多是因為一直在等研究證據出現來支持我的觀點（畢竟有一分證據才...

translational medicine 在 中央研究院 Academia Sinica Facebook 的精選貼文

中央研究院 Academia Sinica By 中央研究院 Academia Sinica

2021-03-27 21:00:57 有 809 人按讚
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#胰臟癌👫 #標靶治療🎯 開發 #抗癌藥物 15年磨一劍 想想那台 #小挖土機🚢 ⛏
　　
胰臟癌是相當棘手的癌症，確診時，患者的腫瘤細胞通常已經轉移，增加治療難度...
　　
當年 #臺大醫院 醫師與本院 #李文華 院士分享臨床治療心得時，李院士意識到：若能結合臨床經驗與科學研究，有助於解決這個攸關全人類健康的重大問題，挽救更多生命！
　　
―
在李文華院士帶領下，由本院 #基因體研究中心、中國醫藥大學新藥開發中心組成的跨機構研究團隊，歷經多年研究，於今（2021）年宣布👉破解胰臟癌細胞的訊息傳遞機制，並且合成出 #多胜肽分子，可以 #阻斷致癌訊號傳遞，#抑制癌細胞的生長與轉移。

🎯實驗顯示能有效延長胰臟癌小鼠的壽命，而且不會影響正常的免疫反應。研究成果已發表在國際期刊《科學轉譯醫學》（Science Translational Medicine）
　
―
💥原來，在胰臟癌細胞表面大量出現的受體（存在於細胞膜上的蛋白質分子）「IL-17RB」，容易兩兩結合，形成同質雙聚體，遇到配體IL-17B後，就會召喚激酶「MLK4」，催化蛋白質磷酸化，有如按下開關般，啟動後續一連串致癌訊號🔔 🔔 🔔
　　
為了阻斷癌化訊號傳遞🔕🔕🔕，研究團隊設計出多胜肽分子，它是一組胺基酸序列，可在細胞內特定位置取代激酶MLK4，阻止激酶與受體交互作用。相較於團隊2015年研發出的抗體藥物，治療更為精準，而且不影響患者免疫力。

目前團隊致力研發效果更穩定的 #小分子藥物，以利胰臟癌患者進行 #標靶治療。
　　
🔴新聞稿：https://reurl.cc/v5oAoo
―
Pancreatic cancer is known to be vicious, pancreatic ductal adenocarcinoma (PDAC) is the type that accounts for 95% of pancreatic cancer and so far it is still incurable. An added fact makes PDAC doomed lies in its tendency to have metastasis, meaning cancer cells have already spread to other organs, when diagnosed.
　　
In this study, “The results not only establish a clear pathway of how proximal signaling of IL-17RB occurs, but also provides insight into how this pathway is clinically significant in many pancreatic cancers.”, commented Dr. Chun-Mei Hu.
　　
🔴Press Release：https://reurl.cc/dV9A8g
―
　　
研究團隊成員：中央研究院李文華院士、胡春美助研究員和沈家寧副研究員；中國醫藥大學吳恒祥助理教授；臺大醫院田郁文醫師、張毓廷醫師、章明珠醫師和鄭永銘醫師。👏👏👏
　　
Team members are from Academia Sinica (Dr. Wen-Hwa Lee, Dr. Chun-Mei Hu and Dr. Chia-Ning Shen), China Medical University (Dr. Heng-Hsiung Wu) and National Taiwan University physicians (Dr. Yu-Wen Tien, Dr. Yu-Ting Chang, Dr. Ming-Chu Chang and Dr. Yung-Ming Jeng.👏👏👏

#研究團隊十五年青春 #迎戰癌中之王 #存活率最低的癌症

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中央研究院 Academia Sinica

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這裡是由【中央研究院媒體小組】經營的平台，作為中研院好朋友們交流互動用，幾點注意事項還請粉絲們彼此提醒喲！ ＊發文請盡可能與學術研究、學術活動相關，勿濫用平台打廣告。 ＊有疑慮要發問，請保持基本禮貌，尊重自己也尊重別人。 ＊歡迎各種評論，但禁止謾罵或人身攻擊等，違者將隱藏、刪除貼文或封鎖帳號。 ＊有非關本文的意見，請善用「塗鴉牆」或「私訊」，發文下明顯不相干留言將隱藏或刪除，保持版面一致性。
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translational medicine 在 運動營養師 楊承樺 Facebook 的最佳解答

運動營養師 楊承樺 By 運動營養師 楊承樺

2021-03-04 21:37:46 有 64 人按讚
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（發1篇影片要看超過20幾篇研究文獻再整理出最摘要建議，不幫我追蹤,按讚,分享出去，安內甘丟 ~ XD ）

#168間歇性斷食，運動營養師我也早已實行多年，但過去自己用的配法沒有說太多是因為一直在等研究證據出現來支持我的觀點（畢竟有一分證據才說一分話）。

以前已經有些研究發現若只作斷食而不搭配運動容易掉肌肉，
但這次有更新的研究發現支持下可以來跟大家說：你可以改成168間歇性斷食 搭配 重訓 就可避免掉肌肉還能減脂，但該怎做呢？

今天跟 甜藍蕉 蕉導 拍影片來教大家怎麼安排會更好，並用全家便利商店的 蛋白纖食餐 來示範說明。

對影片中研究有興趣的，我把文獻來源放在最底下。
附註：本次討論針對都是沒有疾病的成年人為對象，若在生病中或有慢性疾病像是糖尿病，或特殊族群例如：學齡青少年、兒童、孕婦、年長者、飲食障礙者、腸胃不適者等等，都不是今天討論的對象。若有其他您不確定的狀況，請先諮詢過您的醫師或營養師意見。
--
#個人運動飲食安排有疑問者建議請先洽詢運動營養師​ #斷食​。
#增肌減脂​ #飲食顧問服務​ #營養講座​
#促進運動表現飲食顧問服務​ #減重​ #減肥​ #運動營養師​ #競技運動營養師​ #營養品顧問​ #拼pin小教室​ #運動營養
#北市大運科所​ #SportsNutrition​ #SportsDietitian​ #SportsScience​
#Inbody570​ #統一陽光豆漿​ #全家健康志向​ #蛋白纖食餐​ #超級大麥​ #運動應援​

文獻來源：
Lowe, D. A., Wu, N., Rohdin-Bibby, L., Moore, A. H., Kelly, N., Liu, Y. E., ... & Weiss, E. J. (2020). Effects of time-restricted eating on weight loss and other metabolic parameters in women and men with overweight and obesity: the TREAT randomized clinical trial. JAMA internal medicine, 180(11), 1491-1499.

Tinsley, G. M., Moore, M. L., Graybeal, A. J., Paoli, A., Kim, Y., Gonzales, J. U., ... & Cruz, M. R. (2019). Time-restricted feeding plus resistance training in active females: a randomized trial. The American journal of clinical nutrition, 110(3), 628-640.

Stratton, M. T., Tinsley, G. M., Alesi, M. G., Hester, G. M., Olmos, A. A., Serafini, P. R., ... & VanDusseldorp, T. A. (2020). Four weeks of time-restricted feeding combined with resistance training does not differentially influence measures of body composition, muscle performance, resting energy expenditure, and blood biomarkers. Nutrients, 12(4), 1126.

Moro, T., Tinsley, G., Bianco, A., Marcolin, G., Pacelli, Q. F., Battaglia, G., ... & Paoli, A. (2016). Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males. Journal of translational medicine, 14(1), 1-10.

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運動營養師 楊承樺

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-豐禾健康管理顧問 總運動營養師 -楊氏診所 顧問營養師 -台北市立大學運動科學研究所碩士 -實踐大學食品營養與保健生技學系 -ACSM(美國運動醫學會)中文CPT(私人教練)證書&講師 -CTSSN台灣運動營養師專業課程認證 -BNI長照分會 會員 -世新大學兼任講師 -台北市體育局運動科學中心暨防護計畫 合作運動營養師 -游泳、排球、網球、競技體操、田徑、羽球、桌球、女子五人制足球國手以及職業選手之運動營養師 -長跑、鐵人三項、空手道菁英組 特約運動營養師 -高雄市體育會空手道委員會 顧問營養師 -嘉義縣武術會、中華金鷹拳總會、嘉義縣體育會國武術競技委員會 顧問營養師 -多家健身房及健身教練特約運動營養師 -澳門澳仕醫療中心最新運動醫學、AFFA美國有氧體適能協會APEX、專任運動教練增能研習…等運動營養講師 -統一陽光 代言營養師 -全家便利商店健康志向鮮食 代言營養師 -美味生活影音料理之美味名人專家 -榮獲 2017 公共健康數位傳播獎 -運動聚落專欄作家暨專家營養師 -運動營養家 顧問營養師 -Joii Sports、運動筆記、華人健康網、女人知己等邀稿作家營養師 -東森幼幼台 料理甜甜圈 顧問營養師 -電視節目、新聞、廣播、健康媒體平台之採訪營養師 -中華民國肥胖研究學會會員 -中華民國糖尿病衛教學會會員 -中華民國營養師公會全國聯合會會員 -台北市營養師公會會員 -台灣運動營養學會會員 -前楊氏生化科技 營養師
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translational medicine 在 Rti 中央廣播電臺 Facebook 的最佳解答

Rti 中央廣播電臺 By Rti 中央廣播電臺

2021-03-04 14:07:11 有 6 人按讚
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【胰臟癌治療露曙光！ 中研院與中醫大合成出胜肽分子有效抑制癌細胞】

胰臟癌確診時，通常約有80%患者的腫瘤細胞已發生轉移，增加治療難度。中央研究院今天(4日)指出，基因體研究中心與中國醫藥大學跨機構研究團隊，破解胰臟癌細胞的訊息傳遞機制，並合成多胜肽分子，可以阻斷致癌訊號傳遞。研究成果已於3月初發表在國際期刊《科學轉譯醫學》（Science Translational Medicine）。

＃胰臟癌
＃胜肽分子
＃中研院
＃中醫大

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中央廣播電臺 (央廣) Radio Taiwan International (RTI)
中央廣播電臺 (央廣) Radio Taiwan International (RTI)
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translational medicine 在 運動營養師 楊承樺 Youtube 的最讚貼文

運動營養師 楊承樺 By 運動營養師 楊承樺

2021-03-04 20:00:16 有 1,424 人看過 有 34 人喜歡
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內容製作產出不易，你的 按讚訂閱分享 是支持我們的動力。
（發1篇影片要看超過20幾篇研究文獻再整理出最摘要建議，不幫我追蹤,按讚,分享出去，
安內甘丟 ~ XD ）
168間歇性斷食，運動營養師我也早已實行多年，但過去自己用的配法沒有說太多是因為一直在等研究證據出現來支持我的觀點（畢竟有一分證據才說一分話）。
以前已經有些研究發現若只作斷食而不搭配運動容易掉肌肉，
但這次有更新的研究發現支持下可以來跟大家說：你可以改成168間歇性斷食 搭配 重訓 就可避免掉肌肉還能減脂，但該怎做呢？
很簡單今天影片來教大家怎麼安排會更好，並用全家便利商店的 蛋白纖食餐
來示範說明。
對影片中研究有興趣的，我把文獻來源放在最底下。
附註：本次討論針對都是沒有疾病的成年人為對象，若在生病中或有慢性疾病像是糖尿病，或特殊族群例如：學齡青少年、兒童、孕婦、年長者、飲食障礙者、腸胃不適者等等，都不是今天討論的對象。若有其他您不確定的狀況，請先諮詢過您的醫師或營養師意見。
--
#個人運動飲食安排有疑問者建議請先洽詢運動營養師 #168 #斷食。
#增肌減脂 #飲食顧問服務 #營養講座 #運動營養
#促進運動表現飲食顧問服務 #減重 #減肥 #運動營養師 #競技運動營養師 #營養品顧問 #拼pin小教室
#北市大運科所 #SportsNutrition #SportsDietitian #SportsScience
#Inbody570 #統一陽光豆漿 #全家健康志向 #蛋白纖食餐 #超級大麥 #運動應援

想看更多營養知識？快按下「訂閱」及小鈴鐺，一有新影片，馬上通知你！
臉書 https://pse.is/N6N95
IG https://pse.is/LDHNQ
YouTube https://pse.is/NG4SH

文獻來源：
Lowe, D. A., Wu, N., Rohdin-Bibby, L., Moore, A. H., Kelly, N., Liu, Y. E., ... & Weiss, E. J. (2020). Effects of time-restricted eating on weight loss and other metabolic parameters in women and men with overweight and obesity: the TREAT randomized clinical trial. JAMA internal medicine, 180(11), 1491-1499.

Tinsley, G. M., Moore, M. L., Graybeal, A. J., Paoli, A., Kim, Y., Gonzales, J. U., ... & Cruz, M. R. (2019). Time-restricted feeding plus resistance training in active females: a randomized trial. The American journal of clinical nutrition, 110(3), 628-640.

Stratton, M. T., Tinsley, G. M., Alesi, M. G., Hester, G. M., Olmos, A. A., Serafini, P. R., ... & VanDusseldorp, T. A. (2020). Four weeks of time-restricted feeding combined with resistance training does not differentially influence measures of body composition, muscle performance, resting energy expenditure, and blood biomarkers. Nutrients, 12(4), 1126.

Moro, T., Tinsley, G., Bianco, A., Marcolin, G., Pacelli, Q. F., Battaglia, G., ... & Paoli, A. (2016). Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males. Journal of translational medicine, 14(1), 1-10.

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運動營養師 楊承樺

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2分運動6分吃還有2分生活。我是你的運動營養師 楊承樺 帶領你將運動營養飲食落實到你的生活裡！ 體驗兼顧飲食與運動跟人生的美好！！ 簡歷： 豐禾健康管理顧問公司 總運動營養師 營養師高等考試 通過 台北市立大學運動科學研究所碩士 ACSM-CASM美國運動醫學會私人教練證照 講師 CTSSN台灣運動營養師專業課程認證 高雄市體育會空手道委員會 顧問營養師。 台北市體育局運動科學中心暨防護計畫 運動營養師 兩岸多家體適能、健身房及健身教練特約運動營養師。 各大電視節目、新聞、健康媒體平台之採訪營養師 粉絲團: https://www.facebook.com/SportsDietitianNeo/ 部落格: http://iamneo2013.pixnet.net/blog IG https://pse.is/LDHNQ
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translational medicine 在 [email protected] Youtube 的精選貼文

FindDocTV@FindDoc.com By [email protected]

2021-02-24 15:00:07 有 29,140 人看過 有 0 人喜歡
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中風與認知障礙症 － 陳鎮中內科專科專科醫生＠FindDoc.com

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（一）中風後會引致認知障礙症？ 00:06

（二）如何延緩認知障礙症的發生及惡化？ 01:30

（三）如何及早發現認知障礙症？ 03:19

(本短片作健康教育之用，並不可取代任何醫療診斷或治療。治療成效因人而異，如有疑問，請向專業醫療人士諮詢。)

參考資料：
1. Sun, J., Tan, L., & Yu, J. (2014). Post-stroke cognitive impairment: epidemiology, mechanisms and management. Annals of translational medicine, 2 8, 80.
2. Alvarez-Sabin, J., & Roman, G. C. (2010). Citicoline in Vascular Cognitive Impairment and Vascular Dementia After Stroke. Stroke, 42(1, Supplement 1). doi:10.1161/strokeaha.110.606509
3. Department of Health. (2020). Dementia. Retrieved March 20, 2020 from https://www.elderly.gov.hk/english/common_health_problems/dementia/dementia.html
4. HKADA. (2020). Treatment. Retrieved March 20, 2020 from https://www.hkada.org.hk/treatment
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translational medicine 在 [email protected] Youtube 的精選貼文

FindDocTV@FindDoc.com By [email protected]

2019-05-20 14:45:46 有 37,198 人看過 有 0 人喜歡
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癌症治理 - 精準醫學 (Precision Medicine) 及次世代定序 (Next Generation Sequencing - NGS) － 李宇聰臨床腫瘤科專科醫生＠FindDoc.com

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FindDoc WeChat : 快徳健康香港 FindDoc

（一）甚麼是「精準醫學」(Precision Medicine)? 00:01

（二）甚麼是次世代定序分析 Next Generation Sequencing (NGS)? 00:57

（三）次世代定序分析 Next Generation Sequencing (NGS) 在癌症治療中擔當甚麼角色? 01:58

（四）在治療肺癌上，會如何應用次世代定序分析 (NGS) ? 02:38

（五）為甚麼次世代定序分析 (NGS) 仍未被廣泛使用? 03:41

(本短片作健康教育之用，並不可取代任何醫療診斷或治療。治療成效因人而異，如有疑問，請向專業醫療人士諮詢。)

參考資料：
1. K. Ferryman, M.Pitcans. What is Precision Medicine: 2018 Contemporary Issues and Concerns Primer. Data & Society
2. G. Casey, D. Conti, R. Haile, D. Duggan. Next generation sequencing and a new era of medicine. Gut 2013; 62:920-932.
3. F. Randy Vogenberg, CI. Barash, M. Pursel. Personalised Medicine Part 1: Evolution and Development into Theranostics. (2010). Pharmacy and Therapeutics. 35(10):560-562, 565-567, 576
4. https://www.cancer.gov/about-cancer/treatment/types/precision-medicine (Assessed on 28 March 2019)
5. S. Ari, M.Arikan. Next-Generation Sequencing: Advantages, Disadvantages, and Future. 2016. Plant Omics: Trends and Applications pp109-135
6. https://www.welgene.com.tw/service/ngs/NGS_overview (Assessed on 1 March 2019)
7. http://163.21.2.100/a004/htm/8/hgp.htm (Assessed on 1 March 2019)
8. Oncogenic driver mutations in lung cancer, Luo, S. Y., & Lam, D. C. (2013). Oncogenic driver mutations in lung cancer. Translational respiratory medicine, 1(1), 6.
9. 原发性肺癌诊疗规范 2018
10. Emmet JJ, et al. Cancer Discov 2017;7:596-609
11. https://www.esmo.org/Guidelines/Lung-and-Chest-Tumours/Metastatic-Non-Small-Cell-Lung-Cancer (Assessed on 1 March)
12. https://www.nccn.org/professionals/physician_gls/pdf/nscl_blocks.pdf (Assessed on 1 March 2019)



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translational medicine 在 Journal of Translational Medicine | Home page 的相關結果

One of the world's leading journals in the field of translational research, Journal of Translational Medicine is dedicated to turning fundamental ... ... <看更多>

translational medicine 在 translational medicine | Britannica 的相關結果

translational medicine, area of research that aims to improve human health and longevity by determining the relevance to human disease of novel discoveries ... ... <看更多>

translational medicine 在 The Ph.D. Program for Translational Medicine - Taipei Medical ... 的相關結果

degree in Translational Medicine awarded from the Taipei Medical University's College of Medical Science and Technology. Fingerprint. Dive into the research ... ... <看更多>

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